And likely one thats not easy to make.

The hottest of topics, though?

Whether taking estrogen protects against cardiovascular disease (i.e., diseases of the heart and blood vessels).

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This fact played a huge part in my deciding to start the therapy.

Thats very important because it means the risk can be modifiable, he adds.

Which begs the question: Can replacing lost estrogen via HRT reduce your cardiovascular disease risk?

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director of the Atherosclerosis Research Unit and professor of cardiology at theKeck School of Medicine USC

Evidence so far points toward yes, but as long as its timed the right way.

Can HRT for menopause benefit your heart?

Theres a possibility it can.

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Why did this happen?

There are a few reasons.

Though estrogen lost atany agecan also pose risks to your heart.

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(More on this below.)

Whens the ideal time to start HRT to maintain heart health?

This is sometimes called the timing hypothesis or window of opportunity.

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director of the Atherosclerosis Research Unit and professor of cardiology at theKeck School of Medicine USC

We dont really understand the biology behind the mechanisms of this window of opportunity, says Dr. Hodis.

This is basically like making a phone call that never gets received or answered.

Where does this leave transdermal estrogen (i.e., the kind delivered through a skin patch)?

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Who should not take HRT?

She adds that she does not prescribe HRT to women without menopausal symptoms.

In other words, you cant just take estrogen and wipe [all risk] out.

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Be a savvy consumer.

HRT can simply be a supplemental option.

El Khoudary, Samar R et al.

142,25 (2020): e506-e532.

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